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KMID : 1101020190440030118
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Journal of Oral Medicine and Pain
2019 Volume.44 No. 3 p.118 ~ p.122
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Oral Manifestation of Paraneoplastic Pemphigus
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Kim Seurin
Park In-Hee
Park Youn-Jung
Kwon Jeong-Seung
Choi Jong-Hoon
Ahn Hyung-Joon
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Abstract
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Paraneoplastic pemphigus (PNP) is a rare and often fatal autoimmune blistering disease accompanied by both benign and malignant neoplasms. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by PNP patients. Oral ulcers are initial lesions in various autoimmune diseases like pemphigus, bullous pemphigoid, erythema multiforme, graft-versus-host, lichen planus, it does not improved despite of high-dose steroid therapy. We report a-35-year-old female who presented oral ulceration, lip crust and skin lesions. By doing several examinations, such as enzyme-linked immunosorbent assay, incisional biopsy with indirect immunofluorescence, she was diagnosed PNP with non-Hodgkin’s lymphoma on pancreas.
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KEYWORD
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Enzyme-linked immunosorbent assay, Fluorescent antibody technique, indirect, Oral ulcer, Pemphigus
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